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antiobesity Discovery of a sensor in cells produce growth hormone digital Schot

SPANISH INVESTIGATORS discovered antiobesity sensor in the cells that produce growth hormone
DirectorioEstados UnidosMasa corporalInvestigación body mass BiomédicaÍndice
MADRID, 25 Mar. (EUROPA PRESS) -
Researchers at the Department of Cell Biology University of Córdoba, in collaboration with the University of Illinois at Chicago (USA) have discovered a natural sensor against the accumulation of fat in the cells that produce growth hormone. This finding, published in 'Endocrinology,' could unlock the secret to combat obesity.
Studies
developed in transgenic mice have shown that the cells that produce growth hormone - somatotroph cells - also function as natural sensors that detect the presence of excess nutrients and inform the body to prevent an accumulation of fat and impaired glucose preconditions in obesity.
UCO investigators, led by Professor Raul Luque, a member of the Department of Cell Biology, University of Córdoba, have experimented with the elimination of specific genes in these cells.


So, have found decreased levels of growth hormone that occurs naturally in the body with aging - the hormone reaches its greatest presence during puberty and then begins its decline - could be the formula that uses the human body to prevent the emergence of other problems, like diabetes.


When this drop is excessive, the changes occur and appear as obesity diseases caused by the accumulation of fat - a defect in the metabolism - the loss of muscle mass and the onset of diabetes.


Doctor in Biology University of Córdoba and member of the Maimonides Institute for Biomedical Research, Raúl Luque, has worked at the University of Illinois at Chicago. Since his return as a researcher at the Ramon y Cajal in 2008, has directed several doctoral thesis and a draft National Plan for Research on growth hormone and extreme metabolic states such as obesity and anorexia, according to the Plataforma SINC

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